A stimuli-responsive hydrogel for doxorubicin delivery
نویسندگان
چکیده
منابع مشابه
Stimuli-responsive Hydrogel for Drug Delivery
Introduction Hydrogels have been extensively investigated as drug delivery carriers in biomedical applications.The stimuli-responsive hydrogel is generally created when an ionic monomer is incorporated into the hydrogel network, in which the charged group is formed and called fixed charge since its mobility is much less than that of freely mobile ions within the interstitial fluid. In this stud...
متن کاملPolymeric composite membranes for temperature and pH-responsive delivery of doxorubicin hydrochloride
Objective(s): Nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. Temperature and pH-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or pH. The objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...
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The fabrication of freestanding, sub-100 nm-thick, pH-responsive hydrogel membranes with controlled nano-morphology, based on modified poly(hydroxyethyl methacrylate) (PHEMA) is presented. Polymer hydrogel-brush films were first synthesized by surface-initiated atom transfer radical polymerization (SI-ATRP) and subsequently detached from silicon substrates by UV-induced photo-cleavage of a spec...
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Diabetic therapeutics, including insulin and glucagon-like peptide 1 (GLP-1), are essential for diabetic patients to regulate blood glucose levels. However, conventional treatments that are based on subcutaneous injections are often associated with poor glucose control and a lack of patient compliance. In this review, we focus on the different stimuli-responsive systems to deliver therapeutics ...
متن کاملpolymeric composite membranes for temperature and ph-responsive delivery of doxorubicin hydrochloride
objective(s): nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. temperature and ph-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or ph. the objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2010
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2010.06.054